Electronic Resource

Correlation of Leptin Receptor Gene Variation with Blood Pressure and Glucose Level in Type 2 Diabetes Mellitus Subjects of Ternate Population, East of Indonesia

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Introduction: The leptin receptor gene (LEPR) variation plays an important role in diseases related with obesity which include Type 2 Diabetes Mellitus (T2DM) and hypertension in some populations. The role of this variation is

still controversial and not yet studied in the eastern parts of Indonesia. Hence, this study aimed to explore the correlation of leptin receptor variations (Lys109Arg and Gln223Arg) with blood pressure and blood glucose in T2DM in Ternate population. Methods: This study examined 136 subjects with the age range of 32-76 years old. Five mL of fasting blood were taken to determine blood glucose levels using the GOD-PAP method, and leukocytes were used for genotyping by polymerase chain reaction (PCR)-restriction fragment length polymorphism (RFLP) technique methods. Frequencies of genotypes and alleles were analyzed with chi square tests. Correlations of genotypes with the anthropometric measurements were calculated by logistic regression with significance value if p

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Ketersediaan

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Informasi Detail

Judul Seri

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No. Panggil

NONE

Penerbit

Malaysia : Mald Med Health Sci., 2020

Deskripsi Fisik

6 hlm : Ilus

Bahasa

English

ISBN/ISSN

16758544

Klasifikasi

NONE

Tipe Isi

text

Tipe Media

Website

Tipe Pembawa

online resource

Edisi

Vol 16 No 3 Juni 2020

Subjek

Diabetes Mellitus
Jurnal Internasional

Info Detail Spesifik

dapat diakses melalui website

Pernyataan Tanggungjawab

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